APTTV stands for activatedpartial thromboplastin time. This indicator refers to the study of the blood coagulation system and reflects the internal and general way of coagulation, ie, this is the time it takes to form a blood clot. This test is included in a study called coagulogram, which more thoroughly studies the coagulation system.
In this study, the time requiredon clot formation. When testing blood on the APTT, the norm in a healthy person is between 25 and 40 seconds. If other clotting factors (prothrombin, INR, fibrinogen, etc.) change, then the APTT parameter reacts sharply to this. The norm of APTT in the blood of pregnant women is 17-20 seconds.
During pregnancy in the body of a womana number of physiological changes occur. This also applies to blood clotting. The blood of a pregnant woman often becomes more dense. The reason to prescribe a coagulogram study is a change in the general blood test, which, after registration for pregnancy, the woman gives regularly.
If the total blood test showed an increaseshaped elements, this can mean a thickening of the blood, and there is an occasion to prescribe a coagulogram that includes the analysis of the APTT. The rate of this indicator for pregnant women is slightly different and amounts to 17-20 seconds. This is due to the gradual increase in fibrinogen during pregnancy, which at the time of delivery reaches a value of 6 g / l, while in healthy people it is normally between 2.0 and 4.0 g / l.
In the body of a pregnant woman, certain processesare not active, this also applies to hemostasis. This is normal, but deviations from the norm do happen. To avoid possible negative consequences for the child and mother, a coagulogram is prescribed.
Coagulogram research can be basic and advanced. The basic study includes the following parameters:
If necessary, additional parameters can be assigned:
The index of APTT during pregnancy (norm 17-20 sec.), fibrinogen and other parameters, especially at the latest times, are of great importance for the prevention of complications. Thus, an increase in PTI (prothrombin) above 150% may indicate abruption of the placenta. It is very dangerous for the life of the future mother and her child.
D-dimer should normally not be more than 248 ng / ml. This is for healthy people. During pregnancy, its rates increase. By the end of pregnancy can be above the initial value of 3-4 times. This is the norm. The increase in D-dimer more than 4 times from the initial value may indicate a serious pathology - gestosis, and also occurs in pregnant women with diabetes mellitus or severe kidney disease.
One of the many causes of miscarriagepregnancy and miscarriages of different periods is AFS (antiphospholipid syndrome), which is characterized by the formation of arterial and venous thrombosis. To establish such a diagnosis, antibodies to the outer membrane membrane (phospholipids), as well as fibrinogen, D-dimer, prothrombin, and APTTV values are determined. In pregnancy, their norm differs from the normal indices of healthy people.
The main reasons for this activation are as follows:
If during pregnancy studiesshow that the blood is thick, just do not panic. Most likely, the doctor will prescribe a corrective diet. First of all, the salt and all the salted foods (sausages, smoked products, pickled cucumbers, etc.) should be excluded from the diet. From fatty foods is also better to give up. Instead, eat more vegetables, berries and fruits of red and orange. They are more rich in vitamin C than others, which can dilute blood.
It is useful to include in the diet the following products:
Products that can condense blood should be completely eliminated. These include: bananas, potatoes, buckwheat, all fizzy drinks and alcohol.
You need to drink at least 1.5 liters of water a day. But the water must be drinkable and without gas.
One of the most dangerous complications in obstetricpractice is considered DIC-syndrome (deseminirovannoe intravascular coagulation). At the initial stage, there is hypercoagulation (increased coagulation), which is then replaced by hypocoagulation (a decrease in coagulation capacity), which leads to massive blood loss and life threatening. DIC-syndrome often acquires uncontrolled flow, and then it can lead to the death of the woman and her baby.
To avoid this situation,research of coagulogram with mandatory determination of fibrinogen, PTI, APTTV, the norm of which during pregnancy is 17-20 seconds. Usually such examination, if there was no history of complications of previous pregnancies, is prescribed in each trimester. Such studies are made unscheduled in those cases if:
Blood for such research is taken from the vein in the treatment room in the morning on an empty stomach. Pregnant women do this in a women's consultation. For reliable indicators it is necessary to observe several simple conditions:
For the APTT rate, the norm in women and menis between 25 and 40 s. On the basis of sex, it does not differ, only during pregnancy it decreases slightly. Interpretation of the results of the study is carried out only by specialists.
Pregnant women's consultation givenThe study is usually done free of charge provided there is a stamped referral from the doctor. All other citizens, if they wish, can pass such a research fee. Extended coagulogram costs about 3500 rubles. The basic parameters will be cheaper - from 700 to 1300 rubles.
In a survey of a coagulation system, one of theThe main parameters are the APTT index. Its rate is from 25 to 40 seconds. Recall, this parameter shows the time it takes to completely coagulate blood and form a blood clot. If this indicator is below 25 seconds, this fact may indicate a thickening of the blood and the risk of thrombosis. In pregnant women, for APTTV, the norm is 17 to 20 seconds. Usually, this condition during pregnancy does not require treatment and passes after delivery. In addition, a few thicken the blood can iron preparations, which are often prescribed to pregnant women with low hemoglobin figures.
The APTT indicator above the norm cantestify to the presence in a person of a disease such as hemophilia, serious liver disease, such as cirrhosis, or a lack of vitamin K. In addition, an increase in this parameter is observed in the following cases:
Such a study of a coagulation system, like a coagulogram, is useful not only for pregnant women, but for all people. In case of any abnormalities, you need to see a doctor.